Publications
A Tribute to Phil Bourne—Scientist and Human
This Special Issue of Biomolecules, commissioned in honor of Dr. Philip E. Bourne,
focuses on a new field of biomolecular data science. In this brief retrospective paper, we
consider the arc of Phil’s 40-year scientific and professional career, particularly as it relates
to the origins of this new field.
https://www.mdpi.com/2218-273X/13/1/181
A novel 'social contract' - An attempt to harmonize a sponsor's exploratory research with a clinical study participant's data rights
A self-amplifying RNA RSV prefusion-F vaccine elicits potent immunity in pre-exposed and naïve non-human primates
Newly approved subunit and mRNA vaccines for respiratory syncytial virus (RSV) demonstrate effectiveness in preventing severe disease, with protection exceeding 80% primarily through the generation of antibodies. An alternative vaccine platform called... https://www.nature.com/articles/s41467-024-54289-9
OTS 2022
Hardware-accelerated edit distance analysis enables genome-wide identification of oligonucleotide off-target effects.
TIDES Euro Poster
In vitro high throughput screening platform for tissue-specific, endosomal escape constructs as potential peptide conjugates for oligonucleotide therapeutics.
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